Getting treatment for COVID-19

Monocolonal Antibody graphic

If you have tested positive for COVID-19, you may be able to get monoclonal antibody therapy to help you recover. This treatment can help keep you from getting seriously sick and keep you out of the hospital. Monoclonal antibody treatment is available across Colorado.

Who’s eligible for treatment

You might be eligible for treatment if you have tested positive for COVID-19, your symptoms started within the last 10 days, you aren’t hospitalized or on oxygen due to COVID-19, and you are at risk of getting very sick without treatment. Adults and children of all ages, including newborns, may be able to receive monoclonal antibody treatment.  

People at risk of getting very sick include:

  • People who are 65 years old or older.
  • People who are obese or overweight. This includes adults with a BMI of 25 or more. It also includes children under age 18 years old whose providers determine they meet the criteria.
  • Pregnant people.
  • People with certain underlying medical conditions.

Your doctor or health care provider can help you find out if monoclonal antibody treatment is right for you. If you are at high risk and have tested positive, you can seek treatment even if you are fully vaccinated against COVID-19. Monoclonal antibody therapy is not a substitute for vaccination against COVID-19. Getting vaccinated is the best way to keep from getting sick with COVID-19.

How to get treatment

There are three ways to get treatment in Colorado.

  1. Find an appointment at a CDPHE mobile clinic. You must have an appointment to receive treatment at a mobile clinic. Call the COVID-19 hotline at 1-877-CO VAX CO (1-877-268-2926) for help making an appointment. The hotline is available Monday through Friday, 8 a.m. to 8 p.m.; Saturday and Sunday, 9 a.m. to 6 p.m. MT. The call center will be closed on Nov. 25, Dec. 25, and Jan. 1 for the holidays. You can also find a list of upcoming available appointments at COMassVax.org.
  2. Talk with  your doctor or health care provider. Let them know you have tested positive for COVID-19 and want to get monoclonal antibody therapy. If you are eligible, your health care provider will write a prescription for you and help you find a place to get treatment.
  3. Reach out to a health care provider who is offering treatment in Colorado. Click here for a map of places where you can get treatment. You can also find places to get treatment at The National Infusion Center Association or the HHS Protect Locator.
Find a center near you

Click on the name of each site to find upcoming monoclonal antibody therapy appointments. The bus sites are closed on Sundays.

Denver Kaiser Permanente (located in the building) 10350 E Dakota Ave Denver 80247 12/11 - 12/15
Map of infusion centers
Open Embed
How it works

Monoclonal antibody treatment gives you extra antibodies to help fight COVID-19. Your body naturally makes antibodies to fight infection. However, it takes time for your body to make enough antibodies to fight a new virus like COVID-19. Monoclonal antibodies, or mAbs, are made in a laboratory to fight a particular infection—in this case, COVID-19. They are given to patients directly with an infusion to help fight the infection faster than your body could do on its own. 

Early evidence suggests that monoclonal antibody treatment can reduce the amount of the COVID-19 virus in your system. This amount is called “viral load.” Having a lower viral load means you may have milder symptoms, which may make it less likely that you’ll need to go to the hospital.

What to expect at your appointment

Depending on what kind of treatment you get, you may receive your infusion through an IV or as a series of injections under the skin. The IV infusion involves placing a needle in a vein and slowly sending the medicine into the body. It takes about 30 minutes to receive the IV infusion. The injections involve four shots, each one in a different part of your body (for example, your arm or leg). It takes about five to 10 minutes to receive the injections.

No matter what kind of treatment you receive, the provider treating you will ask you to stay in the office for one hour after the infusion or injections to make sure you don’t have an allergic reaction or other side effects that could require medical care. The whole appointment should last about an hour and a half.

Side effects

Antibody treatments may have side effects. Allergic reactions can happen during and after an antibody infusion. Tell your health care provider right away if you get any of the following symptoms of allergic reactions: fever; chills; nausea; headache; shortness of breath; low blood pressure; wheezing; swelling of your lips, face, or throat; rash, including hives; itching; muscle aches; and/or dizziness. 

An infusion of any medicine may cause brief pain, bleeding, bruising of the skin, soreness, swelling, and possible infection at the infusion site.
Talk to your doctor if you experience any side effect that bothers you or does not go away quickly.

More resources